Karazin Physicists Study Polyphenols Against Amyloids: A Step Toward New Strategies for Treating Neurodegenerative Diseases

Researchers from the Education and Research Institute "School of Physics and Technology" at Karazin University are involved in the implementation of a scientific project titled "Biomolecular Interactions of Amyloids: Modulating Influence of Polyphenols." The project aims to identify polyphenolic compounds capable of preventing damage to the structure of functionally important proteins and membranes caused by pathogenic protein aggregates (amyloids). Scientists have identified polyphenols of various classes, as well as their binary and ternary combinations, that possess anti-amyloid properties. The results obtained are crucial for the development of new strategies for the prevention and treatment of neurodegenerative diseases.

The project is being implemented thanks to funding provided through the EURIZON fellowship program, which supports Ukrainian scientists who continue their work under extremely challenging wartime conditions. A key component of this program is also the enhancement of Ukrainian researchers’ integration into the European scientific community and the creation of a foundation for future international collaboration.

This project is being carried out by a team of Ukrainian researchers.

Project Leader:
Valeria Mykhailivna Trusova, Professor, Head of the Department of Medical Physics and Biomedical Nanotechnologies at the School of Physics and Technology, Corresponding Member of the National Academy of Sciences of Ukraine.

Project Participants:
V. N. Karazin Kharkiv National University: Halyna Horbenko, Ulyana Malovytsia.

European Project Partner:
Mette Hedegaard Thomsen, Professor at the School of Engineering and Science, Esbjerg Energy Section, Bioenergy and Bioproducts of Aalborg University, Aalborg, Denmark.